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Acetaldehyde induces cytotoxicity by disrupting mitochondrial function to cause oxidative stress in neural cells (Yan et al., 2022), while acrolein causes DNA damage and oxidative stress in non-neural cells (Hikisz and Jacenik, 2023) and is elevated in the brain of patients with neurodegenerative diseases (Liu et al., 2018

As a result of these facts alone, the FDA should exercise its authority to regulate these addictive products that lead to disease and death, specifically as related to the health of African Americans

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